Prediction of causal candidate genes in coronary artery disease loci

OBJECTIVE: Genome-wide association studies (GWAS) have so far identified 159 significant and suggestive loci for coronary artery disease (CAD). We now report comprehensive bioinformatics analyses of sequence variation in these loci to predict candidate causal genes. APPROACH AND RESULTS: All annotat...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Brænne, Ingrid, Civelek, Mete, Vilne, Baiba, Di Narzo, Antonio, Johnson, Andrew D., Zhao, Yuqi, Reiz, Benedikt, Codoni, Veronica, Webb, Thomas R., Asl, Hassan Foroughi, Hamby, Stephen E., Zeng, Lingyao, Trégouët, David-Alexandre, Hao, Ke, Topol, Eric J., Schadt, Eric E., Yang, Xia, Samani, Nilesh J., Björkegren, Johan L.M., Erdmann, Jeanette, Schunkert, Heribert, Lusis, Aldons J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583353/
https://ncbi.nlm.nih.gov/pubmed/26293461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306108
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