Prediction of causal candidate genes in coronary artery disease loci

OBJECTIVE: Genome-wide association studies (GWAS) have so far identified 159 significant and suggestive loci for coronary artery disease (CAD). We now report comprehensive bioinformatics analyses of sequence variation in these loci to predict candidate causal genes. APPROACH AND RESULTS: All annotat...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Brænne, Ingrid, Civelek, Mete, Vilne, Baiba, Di Narzo, Antonio, Johnson, Andrew D., Zhao, Yuqi, Reiz, Benedikt, Codoni, Veronica, Webb, Thomas R., Asl, Hassan Foroughi, Hamby, Stephen E., Zeng, Lingyao, Trégouët, David-Alexandre, Hao, Ke, Topol, Eric J., Schadt, Eric E., Yang, Xia, Samani, Nilesh J., Björkegren, Johan L.M., Erdmann, Jeanette, Schunkert, Heribert, Lusis, Aldons J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583353/
https://ncbi.nlm.nih.gov/pubmed/26293461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306108
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