Structural implications for the formation and function of the complement effector protein iC3b()

par Papanastasiou, Malvina, Koutsogiannaki, Sophia, Sarigiannis, Yiannis, Geisbrecht, Brian V., Ricklin, Daniel, Lambris, John D.
Publié dans J Immunol (2017)

Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS

par Mullahoo, James, Zhang, Terry, Clauser, Karl, Carr, Steven A., Jaffe, Jacob D., Papanastasiou, Malvina
Publié dans Methods (2020)

The Escherichia coli Peripheral Inner Membrane Proteome

par Papanastasiou, Malvina, Orfanoudaki, Georgia, Koukaki, Marina, Kountourakis, Nikos, Sardis, Marios Frantzeskos, Aivaliotis, Michalis, Karamanou, Spyridoula, Economou, Anastassios
Publié 2013

Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data

par Devaurs, Didier, Antunes, Dinler A., Papanastasiou, Malvina, Moll, Mark, Ricklin, Daniel, Lambris, John D., Kavraki, Lydia E.
Publié dans Front Mol Biosci (2017)

Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling

par Devaurs, Didier, Papanastasiou, Malvina, Antunes, Dinler A, Abella, Jayvee R, Moll, Mark, Ricklin, Daniel, Lambris, John D, Kavraki, Lydia E
Publié dans Int J Comput Biol Drug Des (2018)

Method Development and Validation for the Quantitation of the Complement Inhibitor Cp40 in Human and Cynomolgus Monkey Plasma by UPLC-ESI-MS

par Primikyri, Alexandra, Papanastasiou, Malvina, Sarigiannis, Yiannis, Koutsogiannaki, Sophia, Reis, Edimara S., Tuplano, Joel V., Resuello, Ranillo R. G., Nilsson, Bo, Ricklin, Daniel, Lambris, John D.
Publié dans J Chromatogr B Analyt Technol Biomed Life Sci (2016)

Mass Spectrometry-based Proteomics of Human Cannabinoid Receptor 2: Covalent Cysteine 6.47(257)-Ligand Interaction Affording Megagonist Receptor Activation

par Szymanski, Dennis W., Papanastasiou, Malvina, Melchior, Katja, Zvonok, Nikolai, Mercier, Richard W., Janero, David R., Thakur, Ganesh, Cha, Sangwon, Wu, Billy, Karger, Barry, Makriyannis, Alexandros
Publié 2011

Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS

par Papanastasiou, Malvina, Mullahoo, James, DeRuff, Katherine C., Bajrami, Besnik, Karageorgos, Ioannis, Johnston, Stephen E., Peckner, Ryan, Myers, Samuel A., Carr, Steven A., Jaffe, Jacob D.
Publié dans Mol Cell Proteomics (2019)

Endocannabinoid and Cannabinoid-Like Fatty Acid Amide Levels Correlate with Pain-Related Symptoms in Patients with IBS-D and IBS-C: A Pilot Study

par Fichna, Jakub, Wood, JodiAnne T., Papanastasiou, Malvina, Vadivel, Subramanian K., Oprocha, Piotr, Sałaga, Maciej, Sobczak, Marta, Mokrowiecka, Anna, Cygankiewicz, Adam I., Zakrzewski, Piotr K., Małecka-Panas, Ewa, Krajewska, Wanda M., Kościelniak, Piotr, Makriyannis, Alexandros, Storr, Martin A.
Publié 2013

A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML

par Gopal, Srila, Lu, Qing, Man, Joshua J., Baur, Wendy, Rao, Sitara P., Litichevskiy, Lev, Papanastasiou, Malvina, Creech, Amanda L., DeRuff, Katherine C., Mullahoo, James, Officer, Adam, Egri, Shawn B., Davison, Desiree, Jaffe, Jacob D., Jaffe, Iris Z.
Publié dans Blood Adv (2018)

KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance

par Hinohara, Kunihiko, Wu, Hua-Jun, Vigneau, Sébastien, McDonald, Thomas O., Igarashi, Kyomi J., Yamamoto, Kimiyo N., Madsen, Thomas, Fassl, Anne, Egri, Shawn B., Papanastasiou, Malvina, Ding, Lina, Peluffo, Guillermo, Cohen, Ofir, Kales, Stephen C., Lal-Nag, Madhu, Rai, Ganesha, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Wagle, Nikhil, Brown, Myles, Meissner, Alexander, Sicinski, Piotr, Jaffe, Jacob D., Jeselsohn, Rinath, Gimelbrant, Alexander A., Michor, Franziska, Polyak, Kornelia
Publié dans Cancer Cell (2018)

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

par Hinohara, Kunihiko, Wu, Hua-Jun, Vigneau, Sébastien, McDonald, Thomas O., Igarashi, Kyomi J., Yamamoto, Kimiyo N., Madsen, Thomas, Fassl, Anne, Egri, Shawn B., Papanastasiou, Malvina, Ding, Lina, Peluffo, Guillermo, Cohen, Ofir, Kales, Stephen C., Lal-Nag, Madhu, Rai, Ganesha, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Wagle, Nikhil, Brown, Myles, Meissner, Alexander, Sicinski, Piotr, Jaffe, Jacob D., Jeselsohn, Rinath, Gimelbrant, Alexander A., Michor, Franziska, Polyak, Kornelia
Publié dans Cancer Cell (2019)

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

par Garvie, Colin W., Wu, Xiaoyun, Papanastasiou, Malvina, Lee, Sooncheol, Fuller, James, Schnitzler, Gavin R., Horner, Steven W., Baker, Andrew, Zhang, Terry, Mullahoo, James P., Westlake, Lindsay, Hoyt, Stephanie H., Toetzl, Marcus, Ranaghan, Matthew J., de Waal, Luc, McGaunn, Joseph, Kaplan, Bethany, Piccioni, Federica, Yang, Xiaoping, Lange, Martin, Tersteegen, Adrian, Raymond, Donald, Lewis, Timothy A., Carr, Steven A., Cherniack, Andrew D., Lemke, Christopher T., Meyerson, Matthew, Greulich, Heidi
Publié dans Nat Commun (2021)

Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis

par Rossmann, Marlies P., Hoi, Karen, Chan, Victoria, Abraham, Brian J., Yang, Song, Mullahoo, James, Papanastasiou, Malvina, Wang, Ying, Elia, Ilaria, Perlin, Julie R., Hagedorn, Elliott J., Hetzel, Sara, Weigert, Raha, Vyas, Sejal, Nag, Partha P., Sullivan, Lucas B., Warren, Curtis R., Dorjsuren, Bilguujin, Greig, Eugenia Custo, Adatto, Isaac, Cowan, Chad A., Schreiber, Stuart L., Young, Richard A., Meissner, Alexander, Haigis, Marcia C., Hekimi, Siegfried, Carr, Steven A., Zon, Leonard I.
Publié dans Science (2021)

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

par Litichevskiy, Lev, Peckner, Ryan, Abelin, Jennifer G., Asiedu, Jacob K., Creech, Amanda L., Davis, John F., Davison, Desiree, Dunning, Caitlin M., Egertson, Jarrett D., Egri, Shawn, Gould, Joshua, Ko, Tak, Johnson, Sarah A., Lahr, David L., Lam, Daniel, Liu, Zihan, Lyons, Nicholas J., Lu, Xiaodong, MacLean, Brendan X., Mungenast, Alison E., Officer, Adam, Natoli, Ted E., Papanastasiou, Malvina, Patel, Jinal, Sharma, Vagisha, Toder, Courtney, Tubelli, Andrew A., Young, Jennie Z., Carr, Steven A., Golub, Todd R., Subramanian, Aravind, MacCoss, Michael J., Tsai, Li-Huei, Jaffe, Jacob D.
Publié dans Cell Syst (2018)

Interlaboratory Comparison of Hydrogen–Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb

par Hudgens, Jeffrey W., Gallagher, Elyssia S., Karageorgos, Ioannis, Anderson, Kyle W., Filliben, James J., Huang, Richard Y.-C., Chen, Guodong, Bou-Assaf, George M., Espada, Alfonso, Chalmers, Michael J., Harguindey, Eduardo, Zhang, Hui-Min, Walters, Benjamin T., Zhang, Jennifer, Venable, John, Steckler, Caitlin, Park, Inhee, Brock, Ansgar, Lu, Xiaojun, Pandey, Ratnesh, Chandramohan, Arun, Anand, Ganesh Srinivasan, Nirudodhi, Sasidhar N., Sperry, Justin B., Rouse, Jason C., Carroll, James A., Rand, Kasper D., Leurs, Ulrike, Weis, David D., Al-Naqshabandi, Mohammed A., Hageman, Tyler S., Deredge, Daniel, Wintrode, Patrick L., Papanastasiou, Malvina, Lambris, John D., Li, Sheng, Urata, Sarah
Publié dans Anal Chem (2019)

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 °C and 25.4 °C for the Fab Fragment of NISTmAb

par Hudgens, Jeffrey W., Gallagher, Elyssia S., Karageorgos, Ioannis, Anderson, Kyle W., Huang, Richard Y.-C., Chen, Guodong, Bou-Assaf, George M., Espada, Alfonso, Chalmers, Michael J., Harguindey, Eduardo, Zhang, Hui-Min, Walters, Benjamin T., Zhang, Jennifer, Venable, John, Steckler, Caitlin, Park, Inhee, Brock, Ansgar, Lu, Xiaojun, Pandey, Ratnesh, Chandramohan, Arun, Anand, Ganesh Srinivasan, Nirudodhi, Sasidhar N., Sperry, Justin B., Rouse, Jason C., Carroll, James A., Rand, Kasper D., Leurs, Ulrike, Weis, David D., Al-Naqshabandi, Mohammed A., Hageman, Tyler S., Deredge, Daniel, Wintrode, Patrick L., Papanastasiou, Malvina, Lambris, John D., Li, Sheng, Urata, Sarah
Publié dans J Res Natl Inst Stand Technol (2019)

The Library of Integrated Network-based Cellular Signatures (LINCS) NIH Program: System-level Cataloging of Human Cells Response to Perturbations

par Keenan, Alexandra B., Jenkins, Sherry L., Jagodnik, Kathleen M., Koplev, Simon, He, Edward, Torre, Denis, Wang, Zichen, Dohlman, Anders B., Silverstein, Moshe C., Lachmann, Alexander, Kuleshov, Maxim V., Ma’ayan, Avi, Stathias, Vasileios, Terryn, Raymond, Cooper, Daniel, Forlin, Michele, Koleti, Amar, Vidovic, Dusica, Chung, Caty, Schürer, Stephan C., Vasiliauskas, Jouzas, Pilarczyk, Marcin, Shamsaei, Behrouz, Fazel, Mehdi, Ren, Yan, Niu, Wen, Clark, Nicholas A., White, Shana, Mahi, Naim, Zhang, Lixia, Kouril, Michal, Reichard, John F., Sivaganesan, Siva, Medvedovic, Mario, Meller, Jaroslaw, Koch, Rick J., Birtwistle, Marc R., Iyengar, Ravi, Sobie, Eric A., Azeloglu, Evren, Kaye, Julia, Osterloh, Jeannette, Haston, Kelly, Kalra, Jaslin, Finkbiener, Steve M., Li, Jonathan, Milani, Pamela, Adam, Miriam, Escalante, Renan, Sachs, Karen, Lenail, Alex, Ramamoorthy, Divya, Fraenkel, Ernest, Daigle, Gavin, Hussain, Uzma, Coye, Alyssa, Rothstein, Jeffrey, Sareen, Dhruv, Ornelas, Loren, Banuelos, Maria, Mandefro, Berhan, Ho, Ritchie, Svendsen, Clive N., Lim, Ryan, Stocksdale, Jennifer, Casale, Malcolm, Thompson, Terri, Wu, Jenny, Thompson, Leslie M., Dardov, Victoria, Venkatraman, Vidya, Matlock, Andrea, Van Eyk, Jenny, Jaffe, Jacob D., Papanastasiou, Malvina, Subramanian, Aravind, Golub, Todd R., Erickson, Sean D., Fallahi-Sichani, Mohammad, Hafner, Marc, Gray, Nathanael S., Lin, Jia-Ren, Mills, Caitlin E., Muhlich, Jeremy L., Niepel, Mario, Shamu, Caroline E., Williams, Elizabeth H., Wrobel, David, Sorger, Peter K., Heiser, Laura M., Gray, Joe W., Korkola, James E., Mills, Gordon B., LaBarge, Mark, Feiler, Heidi S., Dane, Mark A., Bucher, Elmar, Nederlof, Michel, Sudar, Damir, Gross, Sean, Kilburn, David F., Smith, Rebecca, Devlin, Kaylyn, Margolis, Ron, Derr, Leslie, Lee, Albert, Pilai, Ajay
Publié dans Cell Syst (2017)