The evolution of the histone methyltransferase gene Su(var)3-9 in metazoans includes a fusion with and a re-fission from a functionally unrelated gene

by Krauss, Veiko, Fassl, Anne, Fiebig, Petra, Patties, Ina, Sass, Heinz
Published 2006

Targeting Aberrant FGFR Signaling to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer

by Sobhani, Navid, Fassl, Anne, Mondani, Giuseppina, Generali, Daniele, Otto, Tobias
Published in Cells (2021)

MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen

by Tagscherer, Katrin E., Fassl, Anne, Sinkovic, Tabea, Richter, Jutta, Schecher, Sabrina, Macher-Goeppinger, Stephan, Roth, Wilfried
Published in Cancer Cell Int (2016)

The requirement for cyclin E in c-Myc overexpressing breast cancers

by Zhou, Yu, Geng, Yan, Zhang, Yujiao, Zhou, Yubin, Chu, Chen, Sharma, Samanta, Fassl, Anne, Butter, Deborah, Sicinski, Piotr
Published in Cell Cycle (2020)

The PEA-15 Protein Regulates Autophagy via Activation of JNK

by Böck, Barbara C., Tagscherer, Katrin E., Fassl, Anne, Krämer, Anika, Oehme, Ina, Zentgraf, Hans-Walter, Keith, Martina, Roth, Wilfried
Published 2010

Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit

by Otto, Tobias, Candido, Sheyla V., Pilarz, Mary S., Sicinska, Ewa, Bronson, Roderick T., Bowden, Michaela, Lachowicz, Iga A., Mulry, Kristin, Fassl, Anne, Han, Richard C., Jecrois, Emmanuelle S., Sicinski, Piotr
Published in Proc Natl Acad Sci U S A (2017)

Targeting the cyclin-dependent kinase 5 in metastatic melanoma

by Sharma, Samanta, Zhang, Tian, Michowski, Wojciech, Rebecca, Vito W., Xiao, Min, Ferretti, Roberta, Suski, Jan M., Bronson, Roderick T., Paulo, Joao A., Frederick, Dennie, Fassl, Anne, Boland, Genevieve M., Geng, Yan, Lees, Jacqueline A., Medema, Rene H., Herlyn, Meenhard, Gygi, Steven P., Sicinski, Piotr
Published in Proc Natl Acad Sci U S A (2020)

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

by Ge, Jennifer Y., Shu, Shaokun, Kwon, Mijung, Jovanović, Bojana, Murphy, Katherine, Gulvady, Anushree, Fassl, Anne, Trinh, Anne, Kuang, Yanan, Heavey, Grace A., Luoma, Adrienne, Paweletz, Cloud, Thorner, Aaron R., Wucherpfennig, Kai W., Qi, Jun, Brown, Myles, Sicinski, Piotr, McDonald, Thomas O., Pellman, David, Michor, Franziska, Polyak, Kornelia
Published in Nat Commun (2020)

Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells

by Johannessen, Liv, Sundberg, Thomas B, O’Connell, Daniel J, Kolde, Raivo, Berstler, James, Billings, Katelyn J, Khor, Bernard, Seashore-Ludlow, Brinton, Fassl, Anne, Russell, Caitlin N, Latorre, Isabel J, Jiang, Baishan, Graham, Daniel B, Perez, Jose R, Sicinski, Piotr, Phillips, Andrew J, Schreiber, Stuart L, Gray, Nathanael S, Shamji, Alykhan F, Xavier, Ramnik J
Published in Nat Chem Biol (2017)

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

by Aranda-Orgilles, Beatriz, Saldaña-Meyer, Ricardo, Wang, Eric, Trompouki, Eirini, Fassl, Anne, Lau, Stephanie, Mullenders, Jasper, Rocha, Pedro P., Raviram, Ramya, Guillamot, María, Sánchez-Díaz, María, Wang, Kun, Kayembe, Clarisse, Zhang, Nan, Amoasii, Leonela, Choudhuri, Avik, Skok, Jane A., Schober, Markus, Reinberg, Danny, Sicinski, Piotr, Schrewe, Heinrich, Tsirigos, Aristotelis, Zon, Leonard I., Aifantis, Iannis
Published in Cell Stem Cell (2016)

Cell Cycle-Targeting MicroRNAs as Therapeutic Tools Against Refractory Cancers

by Hydbring, Per, Wang, Yinan, Fassl, Anne, Li, Xiaoting, Matia, Veronica, Otto, Tobias, Choi, Yoon Jong, Sweeney, Katharine E., Suski, Jan M., Yin, Hao, Bogorad, Roman L., Goel, Shom, Yuzugullu, Haluk, Kauffman, Kevin, Yang, Junghoon, Jin, Chong, Li, Yingxiang, Floris, Davide, Swanson, Richard, Ng, Kimmie, Sicinska, Ewa, Anders, Lars, Zhao, Jean J., Polyak, Kornelia, Anderson, Daniel G., Li, Cheng, Sicinski, Piotr
Published in Cancer Cell (2017)

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

by Fassl, Anne, Brain, Christopher, Abu-Remaileh, Monther, Stukan, Iga, Butter, Deborah, Stepien, Piotr, Feit, Avery S., Bergholz, Johann, Michowski, Wojciech, Otto, Tobias, Sheng, Qing, Loo, Alice, Michael, Walter, Tiedt, Ralph, DeAngelis, Carmine, Schiff, Rachel, Jiang, Baishan, Jovanovic, Bojana, Nowak, Karolina, Ericsson, Maria, Cameron, Michael, Gray, Nathanael, Dillon, Deborah, Zhao, Jean J., Sabatini, David M., Jeselsohn, Rinath, Brown, Myles, Polyak, Kornelia, Sicinski, Piotr
Published in Sci Adv (2020)

KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance

by Hinohara, Kunihiko, Wu, Hua-Jun, Vigneau, Sébastien, McDonald, Thomas O., Igarashi, Kyomi J., Yamamoto, Kimiyo N., Madsen, Thomas, Fassl, Anne, Egri, Shawn B., Papanastasiou, Malvina, Ding, Lina, Peluffo, Guillermo, Cohen, Ofir, Kales, Stephen C., Lal-Nag, Madhu, Rai, Ganesha, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Wagle, Nikhil, Brown, Myles, Meissner, Alexander, Sicinski, Piotr, Jaffe, Jacob D., Jeselsohn, Rinath, Gimelbrant, Alexander A., Michor, Franziska, Polyak, Kornelia
Published in Cancer Cell (2018)

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

by Hinohara, Kunihiko, Wu, Hua-Jun, Vigneau, Sébastien, McDonald, Thomas O., Igarashi, Kyomi J., Yamamoto, Kimiyo N., Madsen, Thomas, Fassl, Anne, Egri, Shawn B., Papanastasiou, Malvina, Ding, Lina, Peluffo, Guillermo, Cohen, Ofir, Kales, Stephen C., Lal-Nag, Madhu, Rai, Ganesha, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Wagle, Nikhil, Brown, Myles, Meissner, Alexander, Sicinski, Piotr, Jaffe, Jacob D., Jeselsohn, Rinath, Gimelbrant, Alexander A., Michor, Franziska, Polyak, Kornelia
Published in Cancer Cell (2019)

Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

by Michowski, Wojciech, Chick, Joel M., Chu, Chen, Kolodziejczyk, Aleksandra, Wang, Yichen, Suski, Jan M., Abraham, Brian, Anders, Lars, Day, Daniel, Dunkl, Lukas M., Man, Mitchell Li Cheong, Zhang, Tian, Laphanuwat, Phatthamon, Bacon, Nickolas A., Liu, Lijun, Fassl, Anne, Sharma, Samanta, Otto, Tobias, Jecrois, Emanuelle, Han, Richard, Sweeney, Katharine E., Marro, Samuele, Wernig, Marius, Geng, Yan, Moses, Alan, Li, Cheng, Gygi, Steven P., Young, Richard A., Sicinski, Piotr
Published in Mol Cell (2020)

Cyclin C is a haploinsufficient tumor suppressor

by Li, Na, Fassl, Anne, Chick, Joel, Inuzuka, Hiroyuki, Li, Xiaoyu, Mansour, Marc R., Liu, Lijun, Wang, Haizhen, King, Bryan, Shaik, Shavali, Gutierrez, Alejandro, Ordureau, Alban, Otto, Tobias, Kreslavsky, Taras, Baitsch, Lukas, Bury, Leah, Meyer, Clifford A., Ke, Nan, Mulry, Kristin A., Kluk, Michael J., Roy, Moni, Kim, Sunkyu, Zhang, Xiaowu, Geng, Yan, Zagozdzon, Agnieszka, Jenkinson, Sarah, Gale, Rosemary E., Linch, David C., Zhao, Jean J., Mullighan, Charles G., Harper, J. Wade, Aster, Jon C., Aifantis, Iannis, von Boehmer, Harald, Gygi, Steven P., Wei, Wenyi, Look, A. Thomas, Sicinski, Piotr
Published in Nat Cell Biol (2014)

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

by Ding, Lina, Su, Ying, Fassl, Anne, Hinohara, Kunihiko, Qiu, Xintao, Harper, Nicholas W., Huh, Sung Jin, Bloushtain-Qimron, Noga, Jovanović, Bojana, Ekram, Muhammad, Zi, Xiaoyuan, Hines, William C., Alečković, Maša, Gil del Alcazar, Carlos, Caulfield, Ryan J., Bonal, Dennis M., Nguyen, Quang-De, Merino, Vanessa F., Choudhury, Sibgat, Ethington, Gabrielle, Panos, Laura, Grant, Michael, Herlihy, William, Au, Alfred, Rosson, Gedge D., Argani, Pedram, Richardson, Andrea L., Dillon, Deborah, Allred, D. Craig, Babski, Kirsten, Kim, Elizabeth Min Hui, McDonnell, Charles H., Wagner, Jon, Rowberry, Ron, Bobolis, Kristie, Kleer, Celina G., Hwang, E. Shelley, Blum, Joanne L., Cristea, Simona, Sicinski, Piotr, Fan, Rong, Long, Henry W., Sukumar, Saraswati, Park, So Yeon, Garber, Judy E., Bissell, Mina, Yao, Jun, Polyak, Kornelia
Published in Nat Commun (2019)