Terpenes and Lipids of the Endocannabinoid and Transient-Receptor-Potential-Channel Biosignaling Systems

ανά Janero, David R., Makriyannis, Alexandros
Τόπος έκδοσης ACS Chem Neurosci (2014)

Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target

ανά Janero, David R., Thakur, Ganesh A.
Τόπος έκδοσης Expert Opin Drug Discov (2016)

Pharmacotherapeutic targeting of the endocannabinoid signaling system: Drugs for obesity and the metabolic syndrome

ανά Vemuri, V. Kiran, Janero, David R., Makriyannis, Alexandros
Έκδοση 2007

Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: Drug-discovery strategies

ανά JANERO, DAVID R., VADIVEL, SUBRAMANIAN K., MAKRIYANNIS, ALEXANDROS
Τόπος έκδοσης Int Rev Psychiatry (2009)

Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

ανά Mallipeddi, Srikrishnan, Janero, David R., Zvonok, Nikolai, Makriyannis, Alexandros
Τόπος έκδοσης Biochem Pharmacol (2016)

Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis

ανά Deshpande, Dipti, Kethireddy, Sravani, Janero, David R., Amiji, Mansoor M.
Τόπος έκδοσης PLoS One (2016)

Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacol...

ανά Karageorgos, Ioannis, Tyukhtenko, Sergiy, Zvonok, Nikolai, Janero, David R., Sallum, Christine, Makriyannis, Alexandros
Έκδοση 2010

Nucleic Acid Delivery for Endothelial Dysfunction in Cardiovascular Diseases

ανά Deshpande, Dipti, Janero, David R., Segura-Ibarra, Victor, Blanco, Elvin, Amiji, Mansoor M.
Τόπος έκδοσης Methodist Debakey Cardiovasc J (2016)

Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: A neuroprotective therapeutic modality

ανά Hwang, Jeannie, Adamson, Crista, Butler, David, Janero, David R., Makriyannis, Alexandros, Bahr, Ben A.
Έκδοση 2009

Human Cannabinoid 1 GPCR C-Terminal Domain Interacts with Bilayer Phospholipids to Modulate the Structure of its Membrane Environment

ανά Tiburu, Elvis K., Tyukhtenko, Sergiy, Zhou, Han, Janero, David R., Struppe, Jochem, Makriyannis, Alexandros
Έκδοση 2011

Human Cannabinoid 2 GPCR Ligand-interaction Landscape: Cysteine Residues Critical to Biarylpyrazole Antagonist Binding Motif and Receptor Modulation

ανά Mercier, Richard W., Pei, Ying, Pandarinathan, Lakshmipathi, Janero, David R., Zhang, Jing, Makriyannis, Alexandros
Έκδοση 2010

Therapeutic modulation of cannabinoid lipid signaling: metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist

ανά Wood, JodiAnne T., Smith, Dustin M., Janero, David R., Zvonok, Alexander M., Makriyannis, Alexandros
Έκδοση 2012

Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments()

ανά Tiburu, Elvis K, Tyukhtenko, Sergiy, Deshmukh, Lalit, Vinogradova, Olga, Janero, David R., Makriyannis, Alexandros
Έκδοση 2009

NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation

ανά Tyukhtenko, Sergiy, Tiburu, Elvis K, Deshmukh, Lalit, Vinogradova, Olga, Janero, David R., Makriyannis, Alexandros
Έκδοση 2009

Mass Spectrometry-Based GPCR Proteomics: Comprehensive Characterization of the Human Cannabinoid 1 Receptor

ανά Zvonok, Nikolai, Xu, Wei, Williams, John, Janero, David R., Krishnan, Srinivasan C., Makriyannis, Alexandros
Έκδοση 2010

Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES

ανά Tyukhtenko, Sergiy, Karageorgos, Ioannis, Rajarshi, Girija, Zvonok, Nikolai, Pavlopoulos, Spiro, Janero, David R., Makriyannis, Alexandros
Τόπος έκδοσης J Biol Chem (2016)

Dynamic Conformational Responses of a Human Cannabinoid Receptor-1 Helix Domain to Its Membrane Environment

ανά Tiburu, Elvis K., Gulla, Stefano V., Tiburu, Mark, Janero, David R., Budil, David E., Makriyannis, Alexandros
Έκδοση 2009

Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma

ανά Wood, JodiAnne T., Williams, John S., Pandarinathan, Lakshmipathi, Janero, David R., Lammi-Keefe, Carol J., Makriyannis, Alexandros
Έκδοση 2010

Differential nitros(yl)ation of blood and tissue constituents during glyceryl trinitrate biotransformation in vivo

ανά Janero, David R., Bryan, Nathan S., Saijo, Fumito, Dhawan, Vijay, Schwalb, David J., Warren, Michael C., Feelisch, Martin
Έκδοση 2004

Solid-state NMR and molecular dynamics characterization of cannabinoid receptor-1 (CB1) helix 7 conformational plasticity in model membranes

ανά Tiburu, Elvis K., Bowman, Anna L., Struppe, Jochem O., Janero, David R., Avraham, Hava K., Makriyannis, Alexandros
Έκδοση 2009