Human Cannabinoid 1 GPCR C-Terminal Domain Interacts with Bilayer Phospholipids to Modulate the Structure of its Membrane Environment

G protein-coupled receptors (GPCRs) play critical physiological and therapeutic roles. The human cannabinoid 1 GPCR (hCB1) is a prime pharmacotherapeutic target for addiction and cardiometabolic disease. Our prior biophysical studies on the structural biology of a synthetic peptide representing the...

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Detaylı Bibliyografya
Asıl Yazarlar: Tiburu, Elvis K., Tyukhtenko, Sergiy, Zhou, Han, Janero, David R., Struppe, Jochem, Makriyannis, Alexandros
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032089/
https://ncbi.nlm.nih.gov/pubmed/21234731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9244-7
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