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Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

The phenomenon of functional selectivity, whereby a ligand preferentially directs the information output of a G-protein coupled receptor (GPCR) along (a) particular effector pathway(s) and away from others, has redefined traditional GPCR signaling paradigms to provide a new approach to structure-bas...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Mallipeddi, Srikrishnan, Janero, David R., Zvonok, Nikolai, Makriyannis, Alexandros
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470118/
https://ncbi.nlm.nih.gov/pubmed/27890725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.11.014
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