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Structural implications for the formation and function of the complement effector protein iC3b()
Complement-mediated opsonization, phagocytosis, and immune stimulation are critical processes in host defense and homeostasis, with the complement activation fragment iC3b playing a key effector role. To date, however, there is no high-resolution structure of iC3b, and some aspects of its structure-...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478675/ https://ncbi.nlm.nih.gov/pubmed/28258193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601864 |
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