Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

Recent genome-wide association studies (GWAS) have identified multiple new loci which appear to alter coronary artery disease (CAD) risk via arterial wall-specific mechanisms. One of the annotated genes encodes LMOD1 (Leiomodin 1), a member of the actin filament nucleator family that is highly enric...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Nanda, Vivek, Wang, Ting, Pjanic, Milos, Liu, Boxiang, Nguyen, Trieu, Matic, Ljubica Perisic, Hedin, Ulf, Koplev, Simon, Ma, Lijiang, Franzén, Oscar, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Montgomery, Stephen B., Snyder, Michael P., Quertermous, Thomas, Leeper, Nicholas J., Miller, Clint L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268002/
https://ncbi.nlm.nih.gov/pubmed/30444878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007755
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