TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells

Both environmental factors and genetic loci have been associated with coronary artery disease (CAD), however gene-gene and gene-environment interactions that might identify molecular mechanisms of risk are not easily studied by human genetic approaches. We have previously identified the transcriptio...

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Pubblicato in:PLoS Genet
Autori principali: Kim, Juyong Brian, Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Iyer, Dharini, Liu, Boxiang, Wang, Ting, Sazonova, Olga, Carcamo-Orive, Ivan, Matic, Ljubica Perisic, Maegdefessel, Lars, Hedin, Ulf, Quertermous, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439967/
https://ncbi.nlm.nih.gov/pubmed/28481916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006750
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