The environment-sensing aryl-hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions

BACKGROUND: Smooth muscle cells (SMC) play a critical role in atherosclerosis. The Aryl hydrocarbon receptor (AHR) is an environment-sensing transcription factor that contributes to vascular development, and has been implicated in coronary artery disease (CAD) risk. We hypothesized that AHR can affe...

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Publicado en:Circulation
Autores principales: Kim, Juyong Brian, Zhao, Quanyi, Nguyen, Trieu, Pjanic, Milos, Cheng, Paul, Wirka, Robert, Travisano, Stanislao, Nagao, Manabu, Kundu, Ramendra, Quertermous, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066499/
https://ncbi.nlm.nih.gov/pubmed/32441123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.045981
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