Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

Although numerous genetic loci have been associated with coronary artery disease (CAD) with genome wide association studies, efforts are needed to identify the causal genes in these loci and link them into fundamental signaling pathways. Recent studies have investigated the disease mechanism of CAD...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Iyer, Dharini, Zhao, Quanyi, Wirka, Robert, Naravane, Ameay, Nguyen, Trieu, Liu, Boxiang, Nagao, Manabu, Cheng, Paul, Miller, Clint L., Kim, Juyong Brian, Pjanic, Milos, Quertermous, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198989/
https://ncbi.nlm.nih.gov/pubmed/30307970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007681
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