Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

Coronary artery disease (CAD) is the leading cause of mortality and morbidity, driven by both genetic and environmental risk factors. Meta-analyses of genome-wide association studies have identified >150 loci associated with CAD and myocardial infarction susceptibility in humans. A majority of th...

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Publicado no:Nat Commun
Main Authors: Miller, Clint L., Pjanic, Milos, Wang, Ting, Nguyen, Trieu, Cohain, Ariella, Lee, Jonathan D., Perisic, Ljubica, Hedin, Ulf, Kundu, Ramendra K., Majmudar, Deshna, Kim, Juyong B., Wang, Oliver, Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Assimes, Themistocles L., Montgomery, Stephen B., Schadt, Eric E., Björkegren, Johan L.M., Quertermous, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941121/
https://ncbi.nlm.nih.gov/pubmed/27386823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12092
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