Dual-Reporter Phenotypic Assay for Human Immunodeficiency Viruses

Por Kajiwara, Keiko, Kodama, Eiichi, Sakagami, Yasuko, Naito, Takeshi, Matsuoka, Masao
Publicado em 2008

In Vitro Induction of Human Immunodeficiency Virus Type 1 Variants Resistant to Phosphoralaninate Prodrugs of Z-Methylenecyclopropane Nucleoside Analogues

Por Yoshimura, Kazuhisa, Feldman, Ron, Kodama, Eiichi, Kavlick, Mark F., Qiu, Yao-Ling, Zemlicka, Jiri, Mitsuya, Hiroaki
Publicado em 1999

Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effect on T-20

Por Izumi, Kazuki, Watanabe, Kentaro, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao, Sarafianos, Stefan G., Kodama, Eiichi N.
Publicado no Antivir Chem Chemother (2011)

Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions

Por Nameki, Daisuke, Kodama, Eiichi, Ikeuchi, Mieko, Mabuchi, Naoto, Otaka, Akira, Tamamura, Hirokazu, Ohno, Mutsuhito, Fujii, Nobutaka, Matsuoka, Masao
Publicado em 2005

Heptad Repeat-Derived Peptides Block Protease-Mediated Direct Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus but Not Entry via the Endosomal Pathway

Por Ujike, Makoto, Nishikawa, Hiroki, Otaka, Akira, Yamamoto, Naoki, Yamamoto, Norio, Matsuoka, Masao, Kodama, Eiichi, Fujii, Nobutaka, Taguchi, Fumihiro
Publicado em 2008

The N348I Mutation at the Connection Subdomain of HIV-1 Reverse Transcriptase Decreases Binding to Nevirapine

Por Schuckmann, Matthew M., Marchand, Bruno, Hachiya, Atsuko, Kodama, Eiichi N., Kirby, Karen A., Singh, Kamalendra, Sarafianos, Stefan G.
Publicado em 2010

In Vitro Anti-Human Immunodeficiency Virus Activities of Z- and E-Methylenecyclopropane Nucleoside Analogues and Their Phosphoro-l-Alaninate Diesters

Por Uchida, Hiroyuki, Kodama, Eiichi N., Yoshimura, Kazuhisa, Maeda, Yosuke, Kosalaraksa, Pope, Maroun, Victor, Qiu, Yao-Ling, Zemlicka, Jiri, Mitsuya, Hiroaki
Publicado em 1999

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons

Por Hatanaka, Yuki, Inoue, Kimiko, Oikawa, Mami, Kamimura, Satoshi, Ogonuki, Narumi, Kodama, Eiichi N., Ohkawa, Yasuyuki, Tsukada, Yu-ichi, Ogura, Atsuo
Publicado no Proc Natl Acad Sci U S A (2015)

Amino Acid Mutation N348I in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Rev...

Por Hachiya, Atsuko, Kodama, Eiichi N., Sarafianos, Stefan G., Schuckmann, Matthew M., Sakagami, Yasuko, Matsuoka, Masao, Takiguchi, Masafumi, Gatanaga, Hiroyuki, Oka, Shinichi
Publicado em 2008

Resistance Profiles of Novel Electrostatically Constrained HIV-1 Fusion Inhibitors

Por Shimura, Kazuya, Nameki, Daisuke, Kajiwara, Keiko, Watanabe, Kentaro, Sakagami, Yasuko, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao, Sarafianos, Stefan G., Kodama, Eiichi N.
Publicado em 2010

K70Q Adds High-Level Tenofovir Resistance to “Q151M Complex” HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism

Por Hachiya, Atsuko, Kodama, Eiichi N., Schuckmann, Matthew M., Kirby, Karen A., Michailidis, Eleftherios, Sakagami, Yasuko, Oka, Shinichi, Singh, Kamalendra, Sarafianos, Stefan G.
Publicado em 2011

SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

Por Naito, Takeshi, Izumi, Kazuki, Kodama, Eiichi, Sakagami, Yasuko, Kajiwara, Keiko, Nishikawa, Hiroki, Watanabe, Kentaro, Sarafianos, Stefan G., Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao
Publicado em 2009

A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo

Por Watanabe, Masahiro, Hashimoto, Koichi, Abe, Yusaku, Kodama, Eiichi N., Nabika, Ryota, Oishi, Shinya, Ohara, Shinichiro, Sato, Masatoki, Kawasaki, Yukihiko, Fujii, Nobutaka, Hosoya, Mitsuaki
Publicado no PLoS One (2016)

Clinical relevance of substitutions in the connection subdomain and RNase H domains of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients

Por Hachiya, Atsuko, Shimane, Kazuki, Sarafianos, Stefan G., Kodama, Eiichi N., Sakagami, Yasuko, Negishi, Fujie, Koizumi, Hirokazu, Gatanaga, Hiroyuki, Matsuoka, Masao, Takiguchi, Masafumi, Oka, Shinichi
Publicado em 2009

Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine

Por Nakata, Hirotomo, Amano, Masayuki, Koh, Yasuhiro, Kodama, Eiichi, Yang, Guangwei, Bailey, Christopher M., Kohgo, Satoru, Hayakawa, Hiroyuki, Matsuoka, Masao, Anderson, Karen S., Cheng, Yung-Chi, Mitsuya, Hiroaki
Publicado em 2007

Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)

Por Shimura, Kazuya, Kodama, Eiichi, Sakagami, Yasuko, Matsuzaki, Yuji, Watanabe, Wataru, Yamataka, Kazunobu, Watanabe, Yasuo, Ohata, Yoshitsugu, Doi, Satoki, Sato, Motohide, Kano, Mitsuki, Ikeda, Satoru, Matsuoka, Masao
Publicado em 2008

HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains

Por Shimane, Kazuki, Kawaji, Kumi, Miyamoto, Fusako, Oishi, Shinya, Watanabe, Kentaro, Sakagami, Yasuko, Fujii, Nobutaka, Shimura, Kazuya, Matsuoka, Masao, Kaku, Mitsuo, Sarafianos, Stefan G., Kodama, Eiichi N.
Publicado em 2013

Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)

Por Salie, Zhe Li, Kirby, Karen A., Michailidis, Eleftherios, Marchand, Bruno, Singh, Kamalendra, Rohan, Lisa C., Kodama, Eiichi N., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Publicado no Proc Natl Acad Sci U S A (2016)

A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impedin...

Por Connell, Bridgette Janine, Chang, Sui-Yuan, Prakash, Ekambaranellore, Yousfi, Rahima, Mohan, Viswaraman, Posch, Wilfried, Wilflingseder, Doris, Moog, Christiane, Kodama, Eiichi N., Clayette, Pascal, Lortat-Jacob, Hugues
Publicado no PLoS One (2016)

Design of Peptide-based Inhibitors for Human Immunodeficiency Virus Type 1 Strains Resistant to T-20

Por Izumi, Kazuki, Kodama, Eiichi, Shimura, Kazuya, Sakagami, Yasuko, Watanabe, Kentaro, Ito, Saori, Watabe, Tsuyoshi, Terakawa, Yukihiro, Nishikawa, Hiroki, Sarafianos, Stefan G., Kitaura, Kazuo, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao
Publicado em 2009