A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation

Amongst the many strategies aiming at inhibiting HIV-1 infection, blocking viral entry has been recently recognized as a very promising approach. Using diverse in vitro models and a broad range of HIV-1 primary patient isolates, we report here that IND02, a type A procyanidin polyphenol extracted fr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Connell, Bridgette Janine, Chang, Sui-Yuan, Prakash, Ekambaranellore, Yousfi, Rahima, Mohan, Viswaraman, Posch, Wilfried, Wilflingseder, Doris, Moog, Christiane, Kodama, Eiichi N., Clayette, Pascal, Lortat-Jacob, Hugues
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082894/
https://ncbi.nlm.nih.gov/pubmed/27788205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165386
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados