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The HIV-1 Envelope Glycoprotein gp120 Features Four Heparan Sulfate Binding Domains, Including the Co-receptor Binding Site

It is well established that the human immunodeficiency virus-1 envelope glycoprotein surface unit, gp120, binds to cell-associated heparan sulfate (HS). Virus infectivity is increased by such interaction, and a variety of soluble polyanions efficiently neutralize immunodeficiency virus-1 in vitro. T...

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書誌詳細
主要な著者: Crublet, Elodie, Andrieu, Jean-Pierre, Vivès, Romain R., Lortat-Jacob, Hugues
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258890/
https://ncbi.nlm.nih.gov/pubmed/18378683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800066200
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