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Metabolic labeling of HIV-1 envelope glycoprotein gp120 to elucidate the effect of gp120 glycosylation on antigen uptake

The glycan shield on the envelope glycoprotein gp120 of HIV-1 has drawn immense attention as a vulnerable site for broadly neutralizing antibodies and for its significant impact on host adaptive immune response to HIV-1. Glycosylation sites and glycan composition/structure at each site on gp120 alon...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Sun, Lina, Ishihara, Mayumi, Middleton, Dustin R., Tiemeyer, Michael, Avci, Fikri Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166730/
https://ncbi.nlm.nih.gov/pubmed/30115684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004798
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