Probing the HIV gp120 Envelope Glycoprotein Conformation by NMR

The HIV envelope glycoprotein gp120 plays a critical role in virus entry, and thus, its structure is of extreme interest for the development of novel therapeutics and vaccines. To date, high resolution structural information about gp120 in complex with gp41 has proven intractable. In this study, we...

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Bibliografiske detaljer
Main Authors: Celigoy, Jessica, Ramirez, Benjamin, Tao, Lin, Rong, Lijun, Yan, Lianying, Feng, Yan-Ru, Quinnan, Gerald V., Broder, Christopher C., Caffrey, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129179/
https://ncbi.nlm.nih.gov/pubmed/21592971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251025
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