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Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41
BACKGROUND: We previously described the construction of an HIV-1 envelope glycoprotein complex (Env) that is stabilized by an engineered intermolecular disulfide bond (SOS) between gp120 and gp41. The modified Env protein antigenically mimics the functional wild-type Env complex. Here, we explore th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC416572/ https://ncbi.nlm.nih.gov/pubmed/15169554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-3 |
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