Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2

Transglutaminase type 2 (TG2) is both a protein cross-linking enzyme and a cell adhesion molecule with an elusive unconventional secretion pathway. In normal conditions, TG2-mediated modification of the extracellular matrix modulates cell motility, proliferation and tissue repair, but under continuo...

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Detalhes bibliográficos
Main Authors: Scarpellini, Alessandra, Germack, Renée, Lortat-Jacob, Hugues, Muramatsu, Takashi, Billett, Ellen, Johnson, Timothy, Verderio, Elisabetta A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709370/
https://ncbi.nlm.nih.gov/pubmed/19398782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012948
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