Inhibition of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis

Proteoglycans (PGs) are composed of a protein moiety and a complex glycosaminoglycan (GAG) polysaccharide moiety. GAG chains are responsible for various biological activities. GAG chains are covalently attached to serine residues of the core protein. The first step in PG biosynthesis is xylosylation...

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Bibliografiske detaljer
Main Authors: Garud, Dinesh R., Tran, Vy M., Victor, Xylophone V., Koketsu, Mamoru, Kuberan, Balagurunathan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570865/
https://ncbi.nlm.nih.gov/pubmed/18708345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805939200
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