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Inhibition of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis

Proteoglycans (PGs) are composed of a protein moiety and a complex glycosaminoglycan (GAG) polysaccharide moiety. GAG chains are responsible for various biological activities. GAG chains are covalently attached to serine residues of the core protein. The first step in PG biosynthesis is xylosylation...

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Bibliografske podrobnosti
Main Authors: Garud, Dinesh R., Tran, Vy M., Victor, Xylophone V., Koketsu, Mamoru, Kuberan, Balagurunathan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570865/
https://ncbi.nlm.nih.gov/pubmed/18708345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805939200
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