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Regulation of Heparan Sulfate and Chondroitin Sulfate Glycosaminoglycan Biosynthesis by 4-Fluoro-glucosamine in Murine Airway Smooth Muscle Cells

The importance of the pathological changes in proteoglycans has driven the need to study and design novel chemical tools to control proteoglycan synthesis. Accordingly, we tested the fluorinated analogue of glucosamine (4-fluoro-N-acetyl-glucosamine (4-F-GlcNAc)) on the synthesis of heparan sulfate...

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書誌詳細
主要な著者: Nigro, Julie, Wang, Aimin, Mukhopadhyay, Durba, Lauer, Mark, Midura, Ronald J., Sackstein, Robert, Hascall, Vincent C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719319/
https://ncbi.nlm.nih.gov/pubmed/19346253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002956
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