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Regulation of Heparan Sulfate and Chondroitin Sulfate Glycosaminoglycan Biosynthesis by 4-Fluoro-glucosamine in Murine Airway Smooth Muscle Cells

The importance of the pathological changes in proteoglycans has driven the need to study and design novel chemical tools to control proteoglycan synthesis. Accordingly, we tested the fluorinated analogue of glucosamine (4-fluoro-N-acetyl-glucosamine (4-F-GlcNAc)) on the synthesis of heparan sulfate...

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Bibliografske podrobnosti
Main Authors: Nigro, Julie, Wang, Aimin, Mukhopadhyay, Durba, Lauer, Mark, Midura, Ronald J., Sackstein, Robert, Hascall, Vincent C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719319/
https://ncbi.nlm.nih.gov/pubmed/19346253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002956
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