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Structural basis of chemokine interactions with heparan sulfate, chondroitin sulfate, and dermatan sulfate

Chemokines play diverse roles in human pathophysiology, ranging from trafficking leukocytes and immunosurveillance to the regulation of metabolism and neural function. Chemokine function is intimately coupled to binding tissue glycosaminoglycans (GAGs), heparan sulfate (HS), chondroitin sulfate (CS)...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Sepuru, Krishna Mohan, Rajarathnam, Krishna
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816105/
https://ncbi.nlm.nih.gov/pubmed/31455633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009879
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