Structural Basis of Chemokine Receptor Function—A Model for Binding Affinity and Ligand Selectivity

Por Rajagopalan, Lavanya, Rajarathnam, Krishna
Publicado em 2006

Isothermal Titration Calorimetry of Membrane Proteins – Progress and Challenges

Por Rajarathnam, Krishna, Rösgen, Jörg
Publicado em 2013

CXCL1/MGSA Is a Novel Glycosaminoglycan (GAG)-binding Chemokine: STRUCTURAL EVIDENCE FOR TWO DISTINCT NON-OVERLAPPING BINDING DOMAINS

Por Sepuru, Krishna Mohan, Rajarathnam, Krishna
Publicado no J Biol Chem (2016)

Thermodynamic characterization of interleukin-8 monomer binding to CXCR1 receptor N-terminal domain

Por Fernando, Harshica, Nagle, Gregg T., Rajarathnam, Krishna
Publicado em 2007

Solution NMR characterization of WT CXCL8 monomer and dimer binding to CXCR1 N-terminal domain

Por Joseph, Prem Raj B, Rajarathnam, Krishna
Publicado no Protein Sci (2015)

Role of Intramolecular Disulfides in Stability and Structure of a Noncovalent Homodimer

Por Rajagopalan, Lavanya, Chin, Christopher C., Rajarathnam, Krishna
Publicado em 2007

Using Isothermal Titration Calorimetry to Determine Thermodynamic Parameters of Protein–Glycosaminoglycan Interactions

Por Dutta, Amit K., Rösgen, Jörg, Rajarathnam, Krishna
Publicado no Methods Mol Biol (2015)

Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics

Por Ravindran, Aishwarya, Joseph, Prem Raj B., Rajarathnam, Krishna
Publicado em 2009

Solution Structure of CXCL5 — A Novel Chemokine and Adipokine Implicated in Inflammation and Obesity

Por Sepuru, Krishna Mohan, Poluri, Krishna Mohan, Rajarathnam, Krishna
Publicado em 2014

Structural Basis of Native CXCL7 Monomer Binding to CXCR2 Receptor N-Domain and Glycosaminoglycan Heparin

Por Brown, Aaron J., Sepuru, Krishna Mohan, Rajarathnam, Krishna
Publicado no Int J Mol Sci (2017)

Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions

Por Sepuru, Krishna Mohan, Nagarajan, Balaji, Desai, Umesh R., Rajarathnam, Krishna
Publicado no J Biol Chem (2016)

Chemokine CXCL1 Dimer Is a Potent Agonist for the CXCR2 Receptor

Por Ravindran, Aishwarya, Sawant, Kirti V., Sarmiento, Jose, Navarro, Javier, Rajarathnam, Krishna
Publicado em 2013

Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding Protein A

Por Morgan, Ashli, Sepuru, Krishna Mohan, Feng, Wei, Rajarathnam, Krishna, Wang, Xu
Publicado no Biochemistry (2015)

Probing Receptor Binding Activity of Interleukin-8 Dimer Using a Disulfide Trap

Por Rajarathnam, Krishna, Prado, Gregory N., Fernando, Harshica, Clark-Lewis, Ian, Navarro, Javier
Publicado em 2006

Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer

Por Poluri, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna
Publicado em 2013

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions

Por Joseph, Prem Raj B., Mosier, Philip D., Desai, Umesh R., Rajarathnam, Krishna
Publicado no Biochem J (2015)

Characterizing protein-glycosaminoglycan interactions using solution NMR Spectroscopy

Por Joseph, Prem Raj B., Poluri, Krishna Mohan, Sepuru, Krishna Mohan, Rajarathnam, Krishna
Publicado no Methods Mol Biol (2015)

Chemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan Interactions

Por Brown, Aaron J., Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna
Publicado no Int J Mol Sci (2017)

Diverging Mechanisms of Activation of Chemokine Receptors Revealed by Novel Chemokine Agonists

Por Sarmiento, Jose, Shumate, Christie, Suetomi, Katsutoshi, Ravindran, Aishwarya, Villegas, León, Rajarathnam, Krishna, Navarro, Javier
Publicado em 2011

The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

Por Gangavarapu, Pavani, Rajagopalan, Lavanya, Kolli, Deepthi, Guerrero-Plata, Antonieta, Garofalo, Roberto P., Rajarathnam, Krishna
Publicado em 2012