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Solution NMR characterization of WT CXCL8 monomer and dimer binding to CXCR1 N-terminal domain
Chemokine CXCL8 and its receptor CXCR1 are key mediators in combating infection and have also been implicated in the pathophysiology of various diseases including chronic obstructive pulmonary disease (COPD) and cancer. CXCL8 exists as monomers and dimers but monomer alone binds CXCR1 with high affi...
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| Publicado no: | Protein Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282414/ https://ncbi.nlm.nih.gov/pubmed/25327289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2590 |
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