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Differential Activation and Regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer
CXCL8 (also known as interleukin-8) activates CXCR1 and CXCR2 to mediate neutrophil recruitment and trigger cytotoxic effect at sites of infection. Under physiological conditions, CXCL8 could exist as monomers, dimers, or a mixture of monomers and dimers. Therefore, both forms of CXCL8 could interac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860795/ https://ncbi.nlm.nih.gov/pubmed/19667085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900305 |
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