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Chemokine CXCL1 Dimer Is a Potent Agonist for the CXCR2 Receptor

The CXCL1/CXCR2 axis plays a crucial role in recruiting neutrophils in response to microbial infection and tissue injury, and dysfunction in this process has been implicated in various inflammatory diseases. Chemokines exist as monomers and dimers, and compelling evidence now exists that both forms...

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Detalhes bibliográficos
Main Authors: Ravindran, Aishwarya, Sawant, Kirti V., Sarmiento, Jose, Navarro, Javier, Rajarathnam, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636908/
https://ncbi.nlm.nih.gov/pubmed/23479735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443762
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