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Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer

Glycosaminoglycan (GAG)-bound and soluble chemokine gradients in the vasculature and extracellular matrix mediate neutrophil recruitment to the site of microbial infection and sterile injury in the host tissue. However, the molecular principles by which chemokine-GAG interactions orchestrate these g...

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Autors principals: Poluri, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757178/
https://ncbi.nlm.nih.gov/pubmed/23864653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492579
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