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Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer

Glycosaminoglycan (GAG)-bound and soluble chemokine gradients in the vasculature and extracellular matrix mediate neutrophil recruitment to the site of microbial infection and sterile injury in the host tissue. However, the molecular principles by which chemokine-GAG interactions orchestrate these g...

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Библиографические подробности
Главные авторы: Poluri, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757178/
https://ncbi.nlm.nih.gov/pubmed/23864653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492579
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