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Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as monomers and dimers, and mediates its function by binding glycosaminoglycans (GAG) and CXCR2 receptor. We recently s...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sawant, Kirti V., Poluri, Krishna Mohan, Dutta, Amit K., Sepuru, Krishna Mohan, Troshkina, Anna, Garofalo, Roberto P., Rajarathnam, Krishna
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021969/
https://ncbi.nlm.nih.gov/pubmed/27625115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33123
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