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Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as monomers and dimers, and mediates its function by binding glycosaminoglycans (GAG) and CXCR2 receptor. We recently s...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Sawant, Kirti V., Poluri, Krishna Mohan, Dutta, Amit K., Sepuru, Krishna Mohan, Troshkina, Anna, Garofalo, Roberto P., Rajarathnam, Krishna
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021969/
https://ncbi.nlm.nih.gov/pubmed/27625115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33123
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