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Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as monomers and dimers, and mediates its function by binding glycosaminoglycans (GAG) and CXCR2 receptor. We recently s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sawant, Kirti V., Poluri, Krishna Mohan, Dutta, Amit K., Sepuru, Krishna Mohan, Troshkina, Anna, Garofalo, Roberto P., Rajarathnam, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021969/
https://ncbi.nlm.nih.gov/pubmed/27625115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33123
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