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Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions

Chemokines play a crucial role in combating microbial infection by recruiting blood neutrophils to infected tissue. In mice, the chemokines Cxcl1/KC and Cxcl2/MIP2 fulfill this role. Cxcl1 and Cxcl2 exist as monomers and dimers, and exert their function by activating the Cxcr2 receptor and binding g...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Sawant, Kirti V., Sepuru, Krishna Mohan, Lowry, Emily, Penaranda, Brigith, Frevert, Charles W., Garofalo, Roberto P., Rajarathnam, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296306/
https://ncbi.nlm.nih.gov/pubmed/32881070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0820-207R
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