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Probing Receptor Binding Activity of Interleukin-8 Dimer Using a Disulfide Trap
Interleukin-8 (IL-8), a member of the chemokine superfamily, exists as both monomers and dimers, and mediates its function by binding to neutrophil CXCR1 and CXCR2 receptors that belong to the G protein-coupled receptor class. It is now well established that the monomer functions as a high-affinity...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518044/ https://ncbi.nlm.nih.gov/pubmed/16784240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0605944 |
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