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Thermodynamic characterization of interleukin-8 monomer binding to CXCR1 receptor N-terminal domain
Chemokines elicit their function by binding receptors of the G-protein-coupled receptor class, and the N-terminal domain (N-domain) of the receptor is one of the two critical ligand-binding sites. In this study, the thermodynamic basis for binding of the chemokine interleukin-8 (IL-8) to the N-domai...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671026/ https://ncbi.nlm.nih.gov/pubmed/17222184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2006.05579.x |
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