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Inhibition of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis
Proteoglycans (PGs) are composed of a protein moiety and a complex glycosaminoglycan (GAG) polysaccharide moiety. GAG chains are responsible for various biological activities. GAG chains are covalently attached to serine residues of the core protein. The first step in PG biosynthesis is xylosylation...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570865/ https://ncbi.nlm.nih.gov/pubmed/18708345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805939200 |
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