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Inhibition of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis

Proteoglycans (PGs) are composed of a protein moiety and a complex glycosaminoglycan (GAG) polysaccharide moiety. GAG chains are responsible for various biological activities. GAG chains are covalently attached to serine residues of the core protein. The first step in PG biosynthesis is xylosylation...

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Main Authors: Garud, Dinesh R., Tran, Vy M., Victor, Xylophone V., Koketsu, Mamoru, Kuberan, Balagurunathan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570865/
https://ncbi.nlm.nih.gov/pubmed/18708345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805939200
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