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Structural diversity of heparan sulfate binding domains in chemokines

Heparan sulfate (HS) molecules are ubiquitous in animal tissues where they function as ligands that are dramatically involved in the regulation of the proteins they bind. Of these, chemokines are a family of small proteins with many biological functions. Their well-conserved monomeric structure can...

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Autori principali: Lortat-Jacob, Hugues, Grosdidier, Aurélien, Imberty, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122172/
https://ncbi.nlm.nih.gov/pubmed/11830659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032497699
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