Driving HIV-1 into a Vulnerable Corner by Taking Advantage of Viral Adaptation and Evolution

Por Harada, Shigeyoshi, Yoshimura, Kazuhisa
Publicado no Front Microbiol (2017)

Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop

Por Yokoyama, Masaru, Naganawa, Satoshi, Yoshimura, Kazuhisa, Matsushita, Shuzo, Sato, Hironori
Publicado em 2012

Increased infectivity in human cells and resistance to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail

Por Kuwata, Takeo, Kaori, Takaki, Enomoto, Ikumi, Yoshimura, Kazuhisa, Matsushita, Shuzo
Publicado em 2013

Amino Acid Insertions near Gag Cleavage Sites Restore the Otherwise Compromised Replication of Human Immunodeficiency Virus Type 1 Variants Resistant to Protease Inhibitors

Por Tamiya, Sadahiro, Mardy, Sek, Kavlick, Mark F., Yoshimura, Kazuhisa, Mistuya, Hiroaki
Publicado em 2004

Impact of V2 Mutations on Escape from a Potent Neutralizing Anti-V3 Monoclonal Antibody during In Vitro Selection of a Primary Human Immunodeficiency Virus Type 1 Isolate

Por Shibata, Junji, Yoshimura, Kazuhisa, Honda, Akiko, Koito, Atsushi, Murakami, Toshio, Matsushita, Shuzo
Publicado em 2007

Impact of antiretroviral pressure on selection of primary human immunodeficiency virus type 1 envelope sequences in vitro

Por Harada, Shigeyoshi, Yoshimura, Kazuhisa, Yamaguchi, Aki, Boonchawalit, Samatchaya, Yusa, Keisuke, Matsushita, Shuzo
Publicado em 2013

Identification of a Key Target Sequence To Block Human Immunodeficiency Virus Type 1 Replication within the gag-pol Transframe Domain

Por Sei, Shizuko, Yang, Quan-en, O'Neill, Dennis, Yoshimura, Kazuhisa, Nagashima, Kunio, Mitsuya, Hiroaki
Publicado em 2000

In Vitro Induction of Human Immunodeficiency Virus Type 1 Variants Resistant to Phosphoralaninate Prodrugs of Z-Methylenecyclopropane Nucleoside Analogues

Por Yoshimura, Kazuhisa, Feldman, Ron, Kodama, Eiichi, Kavlick, Mark F., Qiu, Yao-Ling, Zemlicka, Jiri, Mitsuya, Hiroaki
Publicado em 1999

Enhanced Exposure of Human Immunodeficiency Virus Type 1 Primary Isolate Neutralization Epitopes through Binding of CD4 Mimetic Compounds

Por Yoshimura, Kazuhisa, Harada, Shigeyoshi, Shibata, Junji, Hatada, Makiko, Yamada, Yuko, Ochiai, Chihiro, Tamamura, Hirokazu, Matsushita, Shuzo
Publicado em 2010

Non-Cleavage Site Gag Mutations in Amprenavir-Resistant Human Immunodeficiency Virus Type 1 (HIV-1) Predispose HIV-1 to Rapid Acquisition of Amprenavir Resistance but Delay Develop...

Por Aoki, Manabu, Venzon, David J., Koh, Yasuhiro, Aoki-Ogata, Hiromi, Miyakawa, Toshikazu, Yoshimura, Kazuhisa, Maeda, Kenji, Mitsuya, Hiroaki
Publicado em 2009

In Vitro Anti-Human Immunodeficiency Virus Activities of Z- and E-Methylenecyclopropane Nucleoside Analogues and Their Phosphoro-l-Alaninate Diesters

Por Uchida, Hiroyuki, Kodama, Eiichi N., Yoshimura, Kazuhisa, Maeda, Yosuke, Kosalaraksa, Pope, Maroun, Victor, Qiu, Yao-Ling, Zemlicka, Jiri, Mitsuya, Hiroaki
Publicado em 1999

Conformational Epitope Consisting of the V3 and V4 Loops as a Target for Potent and Broad Neutralization of Simian Immunodeficiency Viruses

Por Kuwata, Takeo, Takaki, Kaori, Yoshimura, Kazuhisa, Enomoto, Ikumi, Wu, Fan, Ourmanov, Ilnour, Hirsch, Vanessa M., Yokoyama, Masaru, Sato, Hironori, Matsushita, Shuzo
Publicado em 2013

A Potent Human Immunodeficiency Virus Type 1 Protease Inhibitor, UIC-94003 (TMC-126), and Selection of a Novel (A28S) Mutation in the Protease Active Site

Por Yoshimura, Kazuhisa, Kato, Ryohei, Kavlick, Mark F., Nguyen, Aline, Maroun, Victor, Maeda, Kenji, Hussain, Khaja A., Ghosh, Arun K., Gulnik, Sergei V., Erickson, John W., Mitsuya, Hiroaki
Publicado em 2002

JE-2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1

Por Yoshimura, Kazuhisa, Kato, Ryohei, Yusa, Keisuke, Kavlick, Mark F., Maroun, Victor, Nguyen, Aline, Mimoto, Tsutomu, Ueno, Takamasa, Shintani, Makoto, Falloon, Judith, Masur, Henry, Hayashi, Hideya, Erickson, John, Mitsuya, Hiroaki
Publicado em 1999

Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247

Por Kirby, Karen A., Ong, Yee Tsuey, Hachiya, Atsuko, Laughlin, Thomas G., Chiang, Leslie A., Pan, Yun, Moran, Jennifer L., Marchand, Bruno, Singh, Kamalendra, Gallazzi, Fabio, Quinn, Thomas P., Yoshimura, Kazuhisa, Murakami, Toshio, Matsushita, Shuzo, Sarafianos, Stefan G.
Publicado no FASEB J (2015)

SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag

Por Ryo, Akihide, Tsurutani, Naomi, Ohba, Kenji, Kimura, Ryuichiro, Komano, Jun, Nishi, Mayuko, Soeda, Hiromi, Hattori, Shinichiro, Perrem, Kilian, Yamamoto, Mikio, Chiba, Joe, Mimaya, Jun-ichi, Yoshimura, Kazuhisa, Matsushita, Shuzo, Honda, Mitsuo, Yoshimura, Akihiko, Sawasaki, Tatsuya, Aoki, Ichiro, Morikawa, Yuko, Yamamoto, Naoki
Publicado em 2008