Chemokine Receptor CXCR4 as a Therapeutic Target for Neuroectodermal Tumors

Por Shim, Hyunsuk, Oishi, Shinya, Fujii, Nobutaka
Publicado em 2008

Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing

Por Tamamura, Hirokazu, Tsutsumi, Hiroshi, Nomura, Wataru, Fujii, Nobutaka
Publicado em 2008

HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent PKA signaling in cultured rat microglia

Por Xu, Changshui, Liu, Jianuo, Chen, Lina, Liang, Shangdong, Fujii, Nobutaka, Tamamura, Hirokazu, Xiong, Huangui
Publicado em 2011

Potent CXCR4 Antagonists Containing Amidine Type Peptide Bond Isosteres

Por Inokuchi, Eriko, Oishi, Shinya, Kubo, Tatsuhiko, Ohno, Hiroaki, Shimura, Kazuya, Matsuoka, Masao, Fujii, Nobutaka
Publicado em 2011

Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effect on T-20

Por Izumi, Kazuki, Watanabe, Kentaro, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao, Sarafianos, Stefan G., Kodama, Eiichi N.
Publicado no Antivir Chem Chemother (2011)

Potent Synergistic Anti-Human Immunodeficiency Virus (HIV) Effects Using Combinations of the CCR5 Inhibitor Aplaviroc with Other Anti-HIV Drugs

Por Nakata, Hirotomo, Steinberg, Seth M., Koh, Yasuhiro, Maeda, Kenji, Takaoka, Yoshikazu, Tamamura, Hirokazu, Fujii, Nobutaka, Mitsuya, Hiroaki
Publicado em 2008

Synthesis and in vitro evaluation of a bimodal CXCR4 antagonistic peptide

Por Kuil, Joeri, Yuan, Hushan, Buckle, Tessa, Oishi, Shinya, Fujii, Nobutaka, Josephson, Lee, van Leeuwen, Fijs W.B.
Publicado em 2011

T134, a Small-Molecule CXCR4 Inhibitor, Has No Cross-Drug Resistance with AMD3100, a CXCR4 Antagonist with a Different Structure

Por Arakaki, Rieko, Tamamura, Hirokazu, Premanathan, Mariappan, Kanbara, Kenji, Ramanan, Sivasundaram, Mochizuki, Katsura, Baba, Masanori, Fujii, Nobutaka, Nakashima, Hideki
Publicado em 1999

Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions

Por Nameki, Daisuke, Kodama, Eiichi, Ikeuchi, Mieko, Mabuchi, Naoto, Otaka, Akira, Tamamura, Hirokazu, Ohno, Mutsuhito, Fujii, Nobutaka, Matsuoka, Masao
Publicado em 2005

Heptad Repeat-Derived Peptides Block Protease-Mediated Direct Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus but Not Entry via the Endosomal Pathway

Por Ujike, Makoto, Nishikawa, Hiroki, Otaka, Akira, Yamamoto, Naoki, Yamamoto, Norio, Matsuoka, Masao, Kodama, Eiichi, Fujii, Nobutaka, Taguchi, Fumihiro
Publicado em 2008

The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7: ROLES OF RECEPTOR DOMAINS

Por Gravel, Stéphanie, Malouf, Camille, Boulais, Philip E., Berchiche, Yamina A., Oishi, Shinya, Fujii, Nobutaka, Leduc, Richard, Sinnett, Daniel, Heveker, Nikolaus
Publicado em 2010

Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gα(i) activation.

Por Berchiche, Yamina A., Chow, Ken Y., Lagane, Bernard, Leduc, Martin, Percherancier, Yann, Fujii, Nobutaka, Tamamura, Hirokazu, Bachelerie, Françoise, Heveker, Nikolaus
Publicado em 2011

The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases

Por Popiel, H. Akiko, Burke, James R., Strittmatter, Warren J., Oishi, Shinya, Fujii, Nobutaka, Takeuchi, Toshihide, Toda, Tatsushi, Wada, Keiji, Nagai, Yoshitaka
Publicado em 2011

Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows

Por NANIWA, Yousuke, NAKATSUKASA, Keisuke, SETSUDA, Shohei, OISHI, Shinya, FUJII, Nobutaka, MATSUDA, Fuko, UENOYAMA, Yoshihisa, TSUKAMURA, Hiroko, MAEDA, Kei-ichiro, OHKURA, Satoshi
Publicado em 2013

Kinesin Spindle Protein Inhibitors with Diaryl Amine Scaffolds: Crystal Packing Analysis for Improved Aqueous Solubility

Por Takeuchi, Tomoki, Oishi, Shinya, Kaneda, Masato, Ohno, Hiroaki, Nakamura, Shinya, Nakanishi, Isao, Yamane, Masayoshi, Sawada, Jun-ichi, Asai, Akira, Fujii, Nobutaka
Publicado em 2014

Resistance Profiles of Novel Electrostatically Constrained HIV-1 Fusion Inhibitors

Por Shimura, Kazuya, Nameki, Daisuke, Kajiwara, Keiko, Watanabe, Kentaro, Sakagami, Yasuko, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao, Sarafianos, Stefan G., Kodama, Eiichi N.
Publicado em 2010

SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

Por Naito, Takeshi, Izumi, Kazuki, Kodama, Eiichi, Sakagami, Yasuko, Kajiwara, Keiko, Nishikawa, Hiroki, Watanabe, Kentaro, Sarafianos, Stefan G., Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao
Publicado em 2009

Synthesis and Biological Evaluation of the [d-MeAla(11)]-Epimer of Coibamide A

Por Nabika, Ryota, Suyama, Takashi L., Hau, Andrew M., Misu, Ryosuke, Ohno, Hiroaki, Ishmael, Jane E., McPhail, Kerry L., Oishi, Shinya, Fujii, Nobutaka
Publicado no Bioorg Med Chem Lett (2014)

A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo

Por Watanabe, Masahiro, Hashimoto, Koichi, Abe, Yusaku, Kodama, Eiichi N., Nabika, Ryota, Oishi, Shinya, Ohara, Shinichiro, Sato, Masatoki, Kawasaki, Yukihiko, Fujii, Nobutaka, Hosoya, Mitsuaki
Publicado no PLoS One (2016)

Prognostic value of metastin expression in human pancreatic cancer

Por Nagai, Kazuyuki, Doi, Ryuichiro, Katagiri, Fumihiko, Ito, Tatsuo, Kida, Atsushi, Koizumi, Masayuki, Masui, Toshihiko, Kawaguchi, Yoshiya, Tomita, Kenji, Oishi, Shinya, Fujii, Nobutaka, Uemoto, Shinji
Publicado em 2009