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Structure–Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide–Polyketides

[Image: see text] Odoamide is a cytotoxic peptide–polyketide hybrid molecule isolated from the Okinawan marine cyanobacterium Okeania sp. For an efficient structure–activity relationship study of the peptide part of odoamide, a facile synthetic protocol was established using a solid-phase peptide sy...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Kaneda, Masato, Kawaguchi, Shinsaku, Fujii, Nobutaka, Ohno, Hiroaki, Oishi, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900340/
https://ncbi.nlm.nih.gov/pubmed/29670702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00028
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