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Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effect on T-20
BACKGROUND: Enfuvirtide (T20), a C-terminal heptad repeat (C-HR)-derived peptide of the human immunodeficiency virus type 1 (HIV-1) glycoprotein, gp41, effectively suppresses HIV-1 replication through a putative mechanism that involves its acting as a decoy and binding to the N-terminal heptad repea...
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| Publicado no: | Antivir Chem Chemother |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4584145/ https://ncbi.nlm.nih.gov/pubmed/21860071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1836 |
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