Design of Peptide-based Inhibitors for Human Immunodeficiency Virus Type 1 Strains Resistant to T-20

Enfuvirtide (T-20) is a fusion inhibitor that suppresses replication of human immunodeficiency virus (HIV) variants with multi-drug resistance to reverse transcriptase and protease inhibitors. It is a peptide derived from the C-terminal heptad repeat (C-HR) of HIV-1 gp41, and it prevents interaction...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Izumi, Kazuki, Kodama, Eiichi, Shimura, Kazuya, Sakagami, Yasuko, Watanabe, Kentaro, Ito, Saori, Watabe, Tsuyoshi, Terakawa, Yukihiro, Nishikawa, Hiroki, Sarafianos, Stefan G., Kitaura, Kazuo, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643509/
https://ncbi.nlm.nih.gov/pubmed/19073606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807169200
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg