Heptad Repeat-Derived Peptides Block Protease-Mediated Direct Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus but Not Entry via the Endosomal Pathway

The peptides derived from the heptad repeat (HRP) of severe acute respiratory syndrome coronavirus (SCoV) spike protein (sHRPs) are known to inhibit SCoV infection, yet their efficacies are fairly low. Recently our research showed that some proteases facilitated SCoV's direct entry from the cel...

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Detalhes bibliográficos
Main Authors: Ujike, Makoto, Nishikawa, Hiroki, Otaka, Akira, Yamamoto, Naoki, Yamamoto, Norio, Matsuoka, Masao, Kodama, Eiichi, Fujii, Nobutaka, Taguchi, Fumihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224400/
https://ncbi.nlm.nih.gov/pubmed/17942557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01697-07
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