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Protease-Mediated Entry via the Endosome of Human Coronavirus 229E

Human coronavirus 229E, classified as a group I coronavirus, utilizes human aminopeptidase N (APN) as a receptor; however, its entry mechanism has not yet been fully elucidated. We found that HeLa cells infected with 229E via APN formed syncytia when treated with trypsin or other proteases but not i...

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Autores principales: Kawase, Miyuki, Shirato, Kazuya, Matsuyama, Shutoku, Taguchi, Fumihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612384/
https://ncbi.nlm.nih.gov/pubmed/18971274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01933-08
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