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Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry

Human coronavirus 229E (HCoV-229E), a causative agent of the common cold, enters host cells via two distinct pathways: one is mediated by cell surface proteases, particularly transmembrane protease serine 2 (TMPRSS2), and the other by endosomal cathepsin L. Thus, specific inhibitors of these proteas...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Shirato, Kazuya, Kanou, Kazuhiko, Kawase, Miyuki, Matsuyama, Shutoku
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165181/
https://ncbi.nlm.nih.gov/pubmed/27733646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01387-16
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