Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing

Seven transmembrane (7TM) G-protein-coupled receptor (GPCR) families are important targets for drug discovery, and specific antagonists for GPCR can accelerate research in the field of medicinal chemistry. The chemokine receptor CXCR4 is a GPCR that possesses a unique ligand CXCL12/stromal cell-deri...

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Bibliographische Detailangaben
Hauptverfasser: Tamamura, Hirokazu, Tsutsumi, Hiroshi, Nomura, Wataru, Fujii, Nobutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2008
Schlagworte:
Perspective
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746577/
https://ncbi.nlm.nih.gov/pubmed/19787093
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