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GXXXG-mediated parallel and antiparallel dimerization of transmembrane helices and its inhibition by cholesterol: Single-pair FRET and 2D IR studies()
Small-residue-mediated interhelical packings are ubiquitously found in helical membrane proteins, although their interaction dynamics and lipid dependence remain mostly uncharacterized. We used a single-pair FRET technique to examine the effect of a GXXXG motif on the association of de-novo designed...
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Publicado no: | Angew Chem Int Ed Engl |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507574/ https://ncbi.nlm.nih.gov/pubmed/28071848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609708 |
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