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GXXXG-mediated parallel and antiparallel dimerization of transmembrane helices and its inhibition by cholesterol: Single-pair FRET and 2D IR studies()

Small-residue-mediated interhelical packings are ubiquitously found in helical membrane proteins, although their interaction dynamics and lipid dependence remain mostly uncharacterized. We used a single-pair FRET technique to examine the effect of a GXXXG motif on the association of de-novo designed...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Yano, Yoshiaki, Kondo, Kotaro, Watanabe, Yuta, Zhang, Tianqi O., Ho, Jia-Jung, Oishi, Shinya, Fujii, Nobutaka, Zanni, Martin T., Matsuzaki, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507574/
https://ncbi.nlm.nih.gov/pubmed/28071848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609708
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