Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)

Integrase (IN), an essential enzyme of human immunodeficiency virus (HIV), is an attractive antiretroviral drug target. The antiviral activity and resistance profile in vitro of a novel IN inhibitor, elvitegravir (EVG) (also known as JTK-303/GS-9137), currently being developed for the treatment of H...

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Detalhes bibliográficos
Main Authors: Shimura, Kazuya, Kodama, Eiichi, Sakagami, Yasuko, Matsuzaki, Yuji, Watanabe, Wataru, Yamataka, Kazunobu, Watanabe, Yasuo, Ohata, Yoshitsugu, Doi, Satoki, Sato, Motohide, Kano, Mitsuki, Ikeda, Satoru, Matsuoka, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224569/
https://ncbi.nlm.nih.gov/pubmed/17977962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01534-07
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