Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis

gan Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Cyhoeddwyd 2011

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

gan Varfolomeev, Eugene, Goncharov, Tatiana, Fedorova, Anna V., Dynek, Jasmin N., Zobel, Kerry, Deshayes, Kurt, Fairbrother, Wayne J., Vucic, Domagoj
Cyhoeddwyd 2008

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

gan Lamkanfi, Mohamed, Mueller, James L., Vitari, Alberto C., Misaghi, Shahram, Fedorova, Anna, Deshayes, Kurt, Lee, Wyne P., Hoffman, Hal M., Dixit, Vishva M.
Cyhoeddwyd 2009

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

gan Goncharov, Tatiana, Niessen, Kyle, de Almagro, Maria Cristina, Izrael-Tomasevic, Anita, Fedorova, Anna V, Varfolomeev, Eugene, Arnott, David, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj
Cyhoeddwyd 2013

Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers

gan Lueck, Sonja C., Russ, Annika C., Botzenhardt, Ursula, Schlenk, Richard F., Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Döhner, Hartmut, Döhner, Konstanze, Fulda, Simone, Bullinger, Lars
Cyhoeddwyd yn Oncotarget (2016)

Novel Bcl-2 Homology-3 Domain-like Sequences Identified from Screening Randomized Peptide Libraries for Inhibitors of the Pro-survival Bcl-2 Proteins

gan Lee, Erinna F., Fedorova, Anna, Zobel, Kerry, Boyle, Michelle J., Yang, Hong, Perugini, Matthew A., Colman, Peter M., Huang, David C. S., Deshayes, Kurt, Fairlie, W. Douglas
Cyhoeddwyd 2009

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

gan Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj
Cyhoeddwyd 2010

Smac Mimetic Bypasses Apoptosis Resistance in FADD- or Caspase-8-Deficient Cells by Priming for Tumor Necrosis Factor α-Induced Necroptosis

gan Laukens, Bram, Jennewein, Claudia, Schenk, Barbara, Vanlangenakker, Nele, Schier, Alexander, Cristofanon, Silvia, Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu JM, Vandenabeele, Peter, Fulda, Simone
Cyhoeddwyd 2011

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP

gan Vucic, Domagoj, Franklin, Matthew C., Wallweber, Heidi J. A., Das, Kanad, Eckelman, Brendan P., Shin, Hwain, Elliott, Linda O., Kadkhodayan, Saloumeh, Deshayes, Kurt, Salvesen, Guy S., Fairbrother, Wayne J.
Cyhoeddwyd 2004

Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals

gan Phu, Lilian, Izrael-Tomasevic, Anita, Matsumoto, Marissa L., Bustos, Daisy, Dynek, Jasmin N., Fedorova, Anna V., Bakalarski, Corey E., Arnott, David, Deshayes, Kurt, Dixit, Vishva M., Kelley, Robert F., Vucic, Domagoj, Kirkpatrick, Donald S.
Cyhoeddwyd 2011

The Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

gan Flygare, John A., Beresini, Maureen, Budha, Nageshwar, Chan, Helen, Chan, Iris T., Cheeti, Sravanthi, Cohen, Frederick, Deshayes, Kurt, Doerner, Karl, Eckhardt, S. Gail, Elliott, Linda O., Feng, Bainian, Franklin, Matthew C., Reisner, Stacy Frankovitz, Gazzard, Lewis, Halladay, Jason, Hymowitz, Sarah G., La, Hank, LoRusso, Patricia, Maurer, Brigitte, Murray, Lesley, Plise, Emile, Quan, Clifford, Stephan, Jean-Philippe, Shin, Young G., Tom, Jeffrey, Tsui, Vickie, Um, Joanne, Varfolomeev, Eugene, Vucic, Domagoj, Wagner, Andrew J., Wallweber, Heidi J.A., Wang, Lan, Ware, Joseph, Wen, Zhaoyang, Wong, Harvey, Wong, Jonathan M., Wong, Melisa, Wong, Susan, Yu, Ron, Zobel, Kerry, Fairbrother, Wayne J.
Cyhoeddwyd 2012

Discovery of a Potent and Selective BCL-X(L) Inhibitor with in Vivo Activity

gan Tao, Zhi-Fu, Hasvold, Lisa, Wang, Le, Wang, Xilu, Petros, Andrew M., Park, Chang H., Boghaert, Erwin R., Catron, Nathaniel D., Chen, Jun, Colman, Peter M., Czabotar, Peter E., Deshayes, Kurt, Fairbrother, Wayne J., Flygare, John A., Hymowitz, Sarah G., Jin, Sha, Judge, Russell A., Koehler, Michael F. T., Kovar, Peter J., Lessene, Guillaume, Mitten, Michael J., Ndubaku, Chudi O., Nimmer, Paul, Purkey, Hans E., Oleksijew, Anatol, Phillips, Darren C., Sleebs, Brad E., Smith, Brian J., Smith, Morey L., Tahir, Stephen K., Watson, Keith G., Xiao, Yu, Xue, John, Zhang, Haichao, Zobel, Kerry, Rosenberg, Saul H., Tse, Chris, Leverson, Joel D., Elmore, Steven W., Souers, Andrew J.
Cyhoeddwyd 2014