A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim

Por Xiang, Song, Callaghan, Matthew M., Watson, Keith G., Tong, Liang
Publicado em 2009

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

Por Holloway, Georgina A., Baell, Jonathan B., Fairlamb, Alan H., Novello, Patrizia M., Parisot, John P., Richardson, John, Watson, Keith G., Street, Ian P.
Publicado em 2006

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library

Por Lackovic, Kurt, Parisot, John P., Sleebs, Nerida, Baell, Jonathan B., Debien, Laurent, Watson, Keith G., Curtis, Joan M., Handman, Emanuela, Street, Ian P., Kedzierski, Lukasz
Publicado em 2010

Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity

Por Holloway, Georgina A., Charman, William N., Fairlamb, Alan H., Brun, Reto, Kaiser, Marcel, Kostewicz, Edmund, Novello, Patrizia M., Parisot, John P., Richardson, John, Street, Ian P., Watson, Keith G., Baell, Jonathan B.
Publicado em 2009

An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus

Por Feil, Susanne C., Hamilton, Stephanie, Krippner, Guy Y., Lin, Bo, Luttick, Angela, McConnell, Darryl B., Nearn, Roland, Parker, Michael W., Ryan, Jane, Stanislawski, Pauline C., Tucker, Simon P., Watson, Keith G., Morton, Craig J.
Publicado em 2012

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Por Macdonald, Simon J. F., Watson, Keith G., Cameron, Rachel, Chalmers, David K., Demaine, Derek A., Fenton, Rob J., Gower, David, Hamblin, J. Nicole, Hamilton, Stephanie, Hart, Graham J., Inglis, Graham G. A., Jin, Betty, Jones, Haydn T., McConnell, Darryl B., Mason, Andy M., Nguyen, Van, Owens, Ian J., Parry, Nigel, Reece, Phillip A., Shanahan, Stephen E., Smith, Donna, Wu, Wen-Yang, Tucker, Simon P.
Publicado em 2004

Structure-Guided Rescaffolding of Selective Antagonists of BCL-X(L)

Por Koehler, Michael F. T., Bergeron, Philippe, Choo, Edna F., Lau, Kevin, Ndubaku, Chudi, Dudley, Danette, Gibbons, Paul, Sleebs, Brad E., Rye, Carl S., Nikolakopoulos, George, Bui, Chinh, Kulasegaram, Sanji, Kersten, Wilhelmus J. A., Smith, Brian J., Czabotar, Peter E., Colman, Peter M., Huang, David C. S., Baell, Jonathan B., Watson, Keith G., Hasvold, Lisa, Tao, Zhi-Fu, Wang, Le, Souers, Andrew J., Elmore, Steven W., Flygare, John A., Fairbrother, Wayne J., Lessene, Guillaume
Publicado em 2014

Discovery of a Potent and Selective BCL-X(L) Inhibitor with in Vivo Activity

Por Tao, Zhi-Fu, Hasvold, Lisa, Wang, Le, Wang, Xilu, Petros, Andrew M., Park, Chang H., Boghaert, Erwin R., Catron, Nathaniel D., Chen, Jun, Colman, Peter M., Czabotar, Peter E., Deshayes, Kurt, Fairbrother, Wayne J., Flygare, John A., Hymowitz, Sarah G., Jin, Sha, Judge, Russell A., Koehler, Michael F. T., Kovar, Peter J., Lessene, Guillaume, Mitten, Michael J., Ndubaku, Chudi O., Nimmer, Paul, Purkey, Hans E., Oleksijew, Anatol, Phillips, Darren C., Sleebs, Brad E., Smith, Brian J., Smith, Morey L., Tahir, Stephen K., Watson, Keith G., Xiao, Yu, Xue, John, Zhang, Haichao, Zobel, Kerry, Rosenberg, Saul H., Tse, Chris, Leverson, Joel D., Elmore, Steven W., Souers, Andrew J.
Publicado em 2014