Screening-Based Translation of Public Research Encounters Painful Problems

Por Baell, Jonathan B.
Publicado no ACS Med Chem Lett (2015)

Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations

Por Baell, Jonathan B., Nissink, J. Willem M.
Publicado no ACS Chem Biol (2017)

Strategies for the Development of Conotoxins as New Therapeutic Leads

Por Brady, Ryan M., Baell, Jonathan B., Norton, Raymond S.
Publicado em 2013

FAF-Drugs3: a web server for compound property calculation and chemical library design

Por Lagorce, David, Sperandio, Olivier, Baell, Jonathan B., Miteva, Maria A., Villoutreix, Bruno O.
Publicado no Nucleic Acids Res (2015)

Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

Por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado em 2012

Correction: Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

Por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado em 2013

Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum

Por Pasaje, Charisse Flerida A., Cheung, Vanessa, Kennedy, Kit, Lim, Erin E., Baell, Jonathan B., Griffin, Michael D. W., Ralph, Stuart A.
Publicado no Sci Rep (2016)

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

Por Holloway, Georgina A., Baell, Jonathan B., Fairlamb, Alan H., Novello, Patrizia M., Parisot, John P., Richardson, John, Watson, Keith G., Street, Ian P.
Publicado em 2006

ω-Conotoxin GVIA Mimetics that Bind and Inhibit Neuronal Ca(v)2.2 Ion Channels

Por Tranberg, Charlotte Elisabet, Yang, Aijun, Vette, Irina, McArthur, Jeffrey R., Baell, Jonathan B., Lewis, Richard J., Tuck, Kellie L., Duggan, Peter J.
Publicado em 2012

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library

Por Lackovic, Kurt, Parisot, John P., Sleebs, Nerida, Baell, Jonathan B., Debien, Laurent, Watson, Keith G., Curtis, Joan M., Handman, Emanuela, Street, Ian P., Kedzierski, Lukasz
Publicado em 2010

Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity

Por Holloway, Georgina A., Charman, William N., Fairlamb, Alan H., Brun, Reto, Kaiser, Marcel, Kostewicz, Edmund, Novello, Patrizia M., Parisot, John P., Richardson, John, Street, Ian P., Watson, Keith G., Baell, Jonathan B.
Publicado em 2009

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the ba...

Por Preston, Sarah, Jiao, Yaqing, Baell, Jonathan B., Keiser, Jennifer, Crawford, Simon, Koehler, Anson V., Wang, Tao, Simpson, Moana M., Kaplan, Ray M., Cowley, Karla J., Simpson, Kaylene J., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Publicado no Int J Parasitol Drugs Drug Resist (2017)

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Por Dahlin, Jayme L., Nelson, Kathryn M., Strasser, Jessica M., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena M., Organ, Shawna, Cuellar, Matthew, Singh, Gurpreet, Shrimp, Jonathan H., Nguyen, Nghi, Meier, Jordan L., Arrowsmith, Cheryl H., Brown, Peter J., Baell, Jonathan B., Walters, Michael A.
Publicado no Nat Commun (2017)

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity

Por Menon, Deepthi, Innes, Ashlee, Oakley, Aaron J., Dahlstrom, Jane E., Jensen, Lora M., Brüstle, Anne, Tummala, Padmaja, Rooke, Melissa, Casarotto, Marco G., Baell, Jonathan B., Nguyen, Nghi, Xie, Yiyue, Cuellar, Matthew, Strasser, Jessica, Dahlin, Jayme L., Walters, Michael A., Burgio, Gaetan, O’Neill, Luke A. J., Board, Philip G.
Publicado no Sci Rep (2017)

Structure-Guided Rescaffolding of Selective Antagonists of BCL-X(L)

Por Koehler, Michael F. T., Bergeron, Philippe, Choo, Edna F., Lau, Kevin, Ndubaku, Chudi, Dudley, Danette, Gibbons, Paul, Sleebs, Brad E., Rye, Carl S., Nikolakopoulos, George, Bui, Chinh, Kulasegaram, Sanji, Kersten, Wilhelmus J. A., Smith, Brian J., Czabotar, Peter E., Colman, Peter M., Huang, David C. S., Baell, Jonathan B., Watson, Keith G., Hasvold, Lisa, Tao, Zhi-Fu, Wang, Le, Souers, Andrew J., Elmore, Steven W., Flygare, John A., Fairbrother, Wayne J., Lessene, Guillaume
Publicado em 2014

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Por Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
Publicado no ACS Cent Sci (2016)