Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

[Image: see text] The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is explored, employing an open sour...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Cent Sci
Egile Nagusiak: Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2016
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084075/
https://ncbi.nlm.nih.gov/pubmed/27800551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00086
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